diff --git a/server/helpers/ffprobe-utils.ts b/server/helpers/ffprobe-utils.ts
index fefed25ae..d2476606e 100644
--- a/server/helpers/ffprobe-utils.ts
+++ b/server/helpers/ffprobe-utils.ts
@@ -262,6 +262,10 @@ async function canDoQuickAudioTranscode (path: string, probe?: ffmpeg.FfprobeDat
   const maxAudioBitrate = getMaxAudioBitrate('aac', audioBitrate)
   if (maxAudioBitrate !== -1 && audioBitrate > maxAudioBitrate) return false
 
+  const channelLayout = parsedAudio.audioStream['channel_layout']
+  // Causes playback issues with Chrome
+  if (!channelLayout || channelLayout === 'unknown') return false
+
   return true
 }